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Research Associate I- Neurogenerative Disease (CRISPR-Cas gene editing) - $2,000sign on bonus

Company: UMass Med School
Location: Worcester
Posted on: January 27, 2023

Job Description:

Research Associate I- Neurogenerative Disease (CRISPR-Cas gene editing) - $2,000 sign on bonus

Minimum Salary


Job Location

3 weeks ago(1/6/2023 5:46 PM)

Requisition Number


# of Openings


Posted Date




Exempt/Non-Exempt Status

Non Union Position -W60- Non Unit Professional


POSITION SUMMARY: We are seeking a Research Associate to work collaboratively on CRISPR-Cas gene editing of the Huntington's Disease (HD) gene. HD is a devasting neurodegenerative disease that currently has no effective treatment. Our goal is to develop gene editing methods to inactivate or correct the disease-causing version of the gene at the DNA level. We are looking for ambitious, hardworking candidates to join this exciting project. There will be opportunities to become familiar with the molecular technologies in gene editing and NextGen sequencing as well as preclinical studies in cell culture and animal models. For an example of a recent study from the lab see https://pubmed.ncbi.nlm.nih.gov/34376056/.



  • Perform laboratory experiments and may be responsible for a single research project
  • Utilize all software relevant to experiment and equipment used
  • Interpret data, form conclusions and decide on next steps under the direction of the PI or designee
  • Maintain accurate records, may modify protocols with the approval of the PI or designee
  • Review literature, publications and grants relevant to assigned projects
  • Record results according to established lab, sponsor & university protocol
  • Assist with performing data analysis and/or mathematical computations
  • Maintain a detailed lab notebook according to lab practice
  • Present findings at lab/group meetings
  • Monitor laboratory supply levels and order as noted
  • Prepare and label buffers, media, solutions, etc.
  • Assist with and comply with all safety regulation and infection control standards
  • Train on IACUC, IRB, EHS, Radiation safety protocols
  • Comply with all applicable state, federal university, and sponsor policies and agreements
  • Provide support with identifying problems and challenges, propose resolutions, implement appropriate solutions
  • Provide support with drafting standard operation procedures in compliance to EHS regulation specific for the lab
  • Perform other duties as required


    • Bachelor's degree in Biological or Natural Science, or equivalent experience
    • Basic understanding of lab safety and protocols
    • Knowledge of Microsoft Office products
    • Ability to analyze data in a quantitative and objective manner.
    • Ability to work in a team environmentSUPERVISION RECEIVED:Under the direction of the Principal Investigator, or designee SUPERVISION EXERCISED: May functionally supervise Lab Technicians and Aides ENVIRONMENTAL WORKING CONDITIONS:Wet chemistry laboratory, and may require appropriate contact with biohazards, radionuclides, toxins, animals, and human specimens.

      Additional Information

      Preferred Qualifications:Some experience with Molecular Biology, Cell culture or mouse studies is preferred, but not essential.

Keywords: UMass Med School, Worcester , Research Associate I- Neurogenerative Disease (CRISPR-Cas gene editing) - $2,000sign on bonus, Advertising , Worcester, Massachusetts

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