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Associate Scientist I/II, Protein Engineering & Characterization

Company: AbbVie
Location: Worcester
Posted on: March 27, 2020

Job Description:

We are seeking a highly motivated and creative scientist with a background in protein engineering, expression, purification and analytical characterization to join the AbbVie Global Biologics Discovery organization. This individual will work in drug discovery cross-functional teams both internally and externally to design, produce, characterize and test recombinant proteins for different therapeutic areas including metabolic diseases, oncology, immunology and aging.Responsibilities:

  • Execute hands on scientific research involving engineering, production and screening of recombinant tool and therapeutic proteins, including antigens, antibodies, fusion proteins and multi-specific biologics.
  • Apply various protein analytical methods to characterize and test recombinant proteins in relevant biochemical and cellular experiments.
  • Work collaboratively with matrixed project teams and members of the Global Biologics Group to drive innovation and deliver novel therapies for patients.
  • Develop productive collaborations and communication with other groups across therapeutic areas.
  • Timely documentation of experiments and activities in electronic archive systems.
  • Engage colleagues in cross-disciplinary scientific discussion, present scientific data to internal and external audiences and publish research in peer-reviewed journals. Position will be hired based on level of experience.
    • Bachelors or Masters degree in biochemistry or related discipline
    • Strong communication and organization skills, especially the ability to work across multiple scientific disciplines and functions. Preferred Experience:
      • Expertise in recombinant protein production, proficiency in analytical techniques for protein characterization (such as mass spectrometry, chromatography and others).
      • Hands-on experience in molecular cloning, and designing/producing novel bi-specific proteins in mammalian and bacterial cells, is highly desired.
      • Proficiency in biochemical assay development including MSD, ForteBio, and receptor ligand interaction assays.
      • Familiarity with molecular modeling.
      • Experience in biochemistry and cellular biology of metalloproteinases.

Keywords: AbbVie, Worcester , Associate Scientist I/II, Protein Engineering & Characterization, Engineering , Worcester, Massachusetts

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