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Senior Scientist, In Vitro Cellular Biologist, Immunology

Company: AbbVie
Location: Worcester
Posted on: January 15, 2020

Job Description:

Our Immunology ADC group located at the AbbVie Bioresearch Center in Worcester, MA is seeking an accomplished myeloid biologist to join the myeloid team to develop innovative myeloid targeted ADCs to alter macrophage and DC functions in autoimmune diseases. As a member of the team, you will identify novel anti-inflammatory payloads and characterize pathogenic myeloid cell populations contributing to autoimmune diseases, to enable precision targeting of myeloid cells and ultimately drive transformation efficacy in Crohn's disease, RA, and fibrosis! In this dynamic and fast paced group, you would be responsible for conceiving of and leading the development of novel myeloid ADCs to achieve project goals. You will make substantial contributions to the conception and execution of in vitro proof-of-concept research in the highly collaborative environment of the broader AbbVie ADC community. Additionally, you will investigate, identify, develop, and optimize new methods and techniques. Furthermore, you will act as a lead myeloid biology scientist on project teams and critically evaluate relevant scientific and regulatory advances and integrate this knowledge into research or development programs.Key Responsibilities Include: Demonstrate the ability to resolve key project hurdles and assumptions by effectively utilizing available information and technical expertiseIndependently design and execute experiments, interpret data, and identify appropriate follow-up strategiesProactively seek out new information in the literature and incorporate this into individual projects as well as the overall programRoutinely demonstrate scientific initiative and creative thinkingSeize opportunities to pursue project relevant leads that are in line with the group's strategyMaintain a high level of productivity in the labOptimally organize and communicate research progress and planned activities through oral and written presentationsPublish research in peer-reviewed journals and present work at scientific conferencesPosition will be hired based on level of experience.Bachelors, Masters, or PhD in Molecular or Cellular Biology, Immunology, or related field with typically 12+ (BS), 10+ (MS) or 0-4+ (PhD) years of experience; Industry experience is highly preferredIn vitro myeloid cell biology, in particular, human/murine primary and cell line culture and assay developmentDevelopment and execution of in vitro and ex vivo human and murine cellular immune assaysMulti-color flow cytometryELISA/MSD, western blotting, and qPCRExperience in ADC, biologic, and/or small molecule therapeutic research in a drug discovery setting, particularly therapeutic screeningExperience in acute in vivo pharmacodynamic modeling of myeloid cell differentiation, function, and migration is preferredExcellent problem-solving skills including critical and analytical thinkingExcellent communication, leadership, and project management skillsDemonstrated scientific writing skills and strong verbal communication skillsProven track record of teamwork, adaptability, innovation, initiative, and integrityAbility to multitask and work within timelinesKey Leadership Competencies:Builds strong relationships with peers and cross functionally with partners outside of the immediate team to enable higher performanceLearns fast, grasps the "essence" and can change course quickly where indicatedRaises the bar and is never satisfied with the status quoCreate a learning environment, open to suggestions and experimentation to drive the science in the field of interestEmbraces the ideas of others, nurtures innovation and manages innovation to reality

Keywords: AbbVie, Worcester , Senior Scientist, In Vitro Cellular Biologist, Immunology, Healthcare , Worcester, Massachusetts

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