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Scientist, Discovery Immunology

Company: AbbVie
Location: Worcester
Posted on: February 15, 2019

Job Description:

We are seeking a highly motivated and talented Scientist for a position in Discovery Immunology in Worcester, MA. A successful candidate should have a strong background in cell biology and immunology. The position offers a unique opportunity for a talented scientist to work in a dynamic, innovative, and multi-disciplinary environment to develop their career at the interface of basic research, target discovery and early drug discovery. The scientist will be responsible for the design, execution, and analysis of immune cell-based assays. The position requires the ability to work independently, have excellent technical, written and oral communication skills and work very well in a team matrix environment. Key Responsibilities:

  • Tissue handling and processing for molecular and cellular phenotyping and functional cellular assay experiments
  • Design, develop, evaluate and implement well-controlled in vitro assays to address target biology and drug biology
  • Planning and coordination of experiments with team members and facility operations.
  • Analysis and presentation of data, providing scientific interpretations and recommendations in lab meetings and project team meetings.
  • Maintaining accurate and well-organized records and laboratory notebook.
  • Supporting the development of protocols, study reports and data presentations Position will be hired based on level of experience.
    • BS, MS in Immunology or related field with typically 5-7+ (BS), or 0-3+ (MS) years of experience
    • BS or MS with a strong research background in molecular and cellular immunology, specifically with working knowledge in fibroblast biology is preferred.
    • General understanding of molecular and transcriptional pathways regulating fibroblast proliferation, differentiation, and activation.
    • Proficient in multi-color flow cytometry - both handling flow cytometer (Fortessa, Canto LSR) and independently analyze the data using analytical software such as FlowJo is required.
    • Extensive tissue culture experience and manipulation of primary cells from mouse or human tissue
    • Experience with culturing and manipulating fibroblast cells
    • Knowledge of in vivo model systems for fibrosis and RA would be a plus.
    • Basic immunological and molecular biology assay skills: Tissue culture, Transfection, ELISA, Western blot, intracellular cytokine analysis, Luciferase assay. Key AbbVie Competencies:
      • Builds strong relationships with peers and cross-functionally with partners outside of the team to enable high performance.
      • Learns fast, grasps the "essence" and can change the course quickly where indicated.
      • Raises the bar and is never satisfied with the status quo.
      • Creates a learning environment, is open to suggestions and experimentation for improvement.
      • Embraces the ideas of others, nurtures innovation and manages innovation to reality. Equal Opportunity Employer Minorities/Women/Veterans/Disabled

        Keywords: AbbVie, Worcester , Scientist, Discovery Immunology, Healthcare , Worcester, Massachusetts

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