Scientist II, Process Development

Company: Astellas
Location: Westborough
Posted on: July 17, 2021

Job Description:

Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians. If you want to be part of this exciting work, you belong at Astellas!

Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at www.astellas.com.

Astellas Institute of Regenerative Medicine (AIRM) is a wholly-owned subsidiary of Astellas Pharma Inc and focused on the development and commercialization of stem cell and regenerative medicine therapies. Astellas is an R&D-driven global pharmaceutical company whose philosophy is to contribute to the improvement of people's heath around the world through the provision of innovative and reliable pharmaceutical products.

AIRM has a world-class R&D team, and is pursuing a diverse range of disease indications, ranging from macular degeneration (currently in clinical trials) and other ocular indications to vascular and autoimmune disease. AIRM's intellectual property portfolio includes pluripotent stem cell platforms -- both embryonic and induced pluripotent stem cells as well as other cell-based therapy research programs. AIRM is headquartered in Massachusetts.

Astellas is announcing a Scientist II, Process Development opportunity at their Astellas Institute of Regenerative Medicine (AIRM) site in Westborough, MA.

Purpose:

Execute studies required to develop and improve upon existing production processes toward the goal of improving performance and increasing yield in the production of cell therapy products.

Essential Job Responsibilities:

* Work closely with other Process Science and Technology (PST) team members, designing and conduct laboratory experiments and tabulate results. * Assist in implementation and scale-up of production processes * Assist in planning and implementing the development of new processing materials, procedures and equipment * Assess equipment and processes to increase yield, purity and function of AIRM's cell products * Prepare study reports * Assist in drafting new and revising existing manufacturing and quality documents * Assist in establishing material specifications and improving manufacturing efficiencies

Organizational Context:

This position reports to the Associate Director of Product Development in the PST group. The individual will work closely with other members of the PST staff and will interact with R&D, Analytical Development and Translational Development groups.

Qualifications:

Required:

* Degree and experience in bioengineering or a life science. BS with 10+, MS with 7+ or PhD with 3+ years' experience. * Broad-based knowledge of cell biology. * Previous experience in process development of cell-based products including expertise in aseptic cell culture processing. * Exceptional oral and written skills.

Preferred:

* Experience with embryonic stem cells, iPS cells and their differentiation. * Experience with disposable manufacturing, scale-up, pilot plant and/or automation. * cGMP experience in mammalian cell-based processing, products and characterization.

Benefits:

* Medical, Dental and Vision Insurance * Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down * 401(k) match and annual company contribution * Company paid life insurance * Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions * Long Term Incentive Plan for eligible positions * Referral bonus program

Astellas is committed to equality of opportunity in all aspects of employment. EOE including Disability/Protected Veterans

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Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled

Keywords: Astellas, Worcester , Scientist II, Process Development, Other , Westborough, Massachusetts