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Scientist II, Translational Development

Company: Astellas
Location: Westborough
Posted on: July 17, 2021

Job Description:

Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians. If you want to be part of this exciting work, you belong at Astellas!

Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at www.astellas.com.

Astellas Institute of Regenerative Medicine (AIRM) is a wholly-owned subsidiary of Astellas Pharma Inc and focused on the development and commercialization of stem cell and regenerative medicine therapies. Astellas is an R&D-driven global pharmaceutical company whose philosophy is to contribute to the improvement of people's heath around the world through the provision of innovative and reliable pharmaceutical products.

AIRM has a world-class R&D team, and is pursuing a diverse range of disease indications, ranging from macular degeneration (currently in clinical trials) and other ocular indications to vascular and autoimmune disease. AIRM's intellectual property portfolio includes pluripotent stem cell platforms -- both embryonic and induced pluripotent stem cells as well as other cell-based therapy research programs. AIRM is headquartered in Massachusetts.

Astellas is announcing a Scientist II, Translational Development opportunity at their Astellas Institute of Regenerative Medicine (AIRM) site in Westborough, MA.


We are seeking a highly motivated scientist to join our team and contribute to and advance the development of cell therapy products. This individual will develop and optimize methods required for production, purification and identification of cell products.

Essential Job Responsibilities:

* Demonstrates solid knowledge of cell biology principles and technical proficiency in research methods. * Develops strategy and technologies to perform experiments and analytical procedures, applying a wide variety of scientific principals and concepts. * Evaluates and defines appropriate approaches. * Contributes to developing and optimizing procedures required for new product scale-up. * Analyzes data, draws conclusions, writes technical reports and makes suggestions based on results of experiments. * Coordinates research efforts and makes key technical contributions. * May lead the design of multiple scientific research studies, including innovative techniques and methodologies. * Maintains accurate records such as notebooks, batch records and electronic entries.

Quantitative Dimensions:

* This position interacts with multiple levels of management and works on complex and diverse problems. * Communicates effectively with line manager and group members * Consistently achieves individual goals * Actions may have implications on manufacturing operation.

Organizational Context:

* Reports to Principal Scientist, Translational Development



* PhD with 3+, MS with 7+ or BS with 10+ years of laboratory experience. * Scientific curiosity * Demonstrated knowledge of cell biology principles. * Impeccable aseptic techniques * Solid working knowledge of cell culture with adherent mammalian cell lines * Expert knowledge of routine molecular assays such as RNA isolation, PCR, immunostaining, flow cytometry, microscopy * Proven ability to efficiently learn new skills


* Ability to maintain accurate records and effectively manage multiple projects * Experience with RNAseq data interpretation (bulk and/or single cell) * Substantial experience with primary cells * Experience with stem cells including pluripotent cells * Attention to detail


* Medical, Dental and Vision Insurance * Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down * 401(k) match and annual company contribution * Company paid life insurance * Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions * Long Term Incentive Plan for eligible positions * Referral bonus program

Astellas is committed to equality of opportunity in all aspects of employment. EOE including Disability/Protected Veterans


Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled

Keywords: Astellas, Worcester , Scientist II, Translational Development, Other , Westborough, Massachusetts

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