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Scientist II/ Senior Scientist I, In Vivo Antibody Discovery

Company: AbbVie
Location: Worcester
Posted on: November 19, 2021

Job Description:

About AbbVieAbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at . on Twitter , Facebook , Instagram , YouTube and LinkedIn .The Biologics Generation Group within Drug Discovery Science and Technology is seeking a highly motivated Research Scientist to join the In Vivo Antibody Discovery team at the AbbVie Bioresearch Center (ABC). The ABC site, based in Worcester, MA, offers the unique setting where Biologics drug discovery, development and manufacturing coexist in one location. Our team interacts with multidisciplinary groups across AbbVie and is focused on developing therapies for Immunology, Neurology and Oncology diseases. We utilize innovative immunization approaches, advanced multiplex screening assays and best-in-class automation platforms to enable successful antibody discovery against complex targets. As an integral part of the group, the ideal candidate will:

  • Exercise proficiencies in mammalian tissue culture, molecular techniques, and binding assays such as ELISA and flow cytometry
  • Execute all phases of in vivo antibody discovery campaigns by hybridoma generation or single cell isolation including immunizations, screening, cell culture and antibody characterization
  • Analyze and document results, placing data in proper scientific context through review of relevant literature and report findings at team meetings
  • Demonstrate scientific excellence through dedication to multiple projects in a fast-paced multi-disciplinary environment
  • Exhibit a can-do attitude with excellent interpersonal and communication skills to multiple teams across different functional areas QualificationsPosition will be hired based on knowledge and/or level of experience.
    • BS, MS or PhD with 7-10 (BS), 5-8 (MS), 0 (PhD) years of experience
    • Experience with aseptic mammalian cell culture
    • Experience in immunoassays using techniques like flow cytometry, ELISA, homogeneous assays and microscopy
    • Knowledge of molecular biology and/or immunology concepts
    • Strong attention to quality and details when exercising organizational, documentation and communication skills
    • Proven flexibility to deal with changing timelines and shifting work priorities
    • Competency with software programs, including MS Excel, PowerPoint, Word Desirable:
      • Experience with microfluidics and single cell analysis
      • Experience with advanced automation platforms and programming
      • Molecular biology techniques including molecular cloning
      • Animal handling experience (e.g. restraint, immunizations, tissue harvesting etc.) Significant Work ActivitiesN/ATravelYes, 5 % of the TimeJob TypeExperiencedScheduleFull-timeJob Level CodeICEqual Employment OpportunityAt AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.

Keywords: AbbVie, Worcester , Scientist II/ Senior Scientist I, In Vivo Antibody Discovery, Other , Worcester, Massachusetts

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