Senior Research Associate, In Vivo

Company: Astellas
Location: Westborough
Posted on: May 28, 2023

Job Description:

Senior Research Associate/Scientist I Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians. If you want to be part of this exciting work, you belong at Astellas! Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at www.astellas.com. Astellas Institute for Regenerative Medicine (AIRM) is a wholly-owned subsidiary of Astellas Pharma Inc and focused on the development and commercialization of stem cell and regenerative medicine therapies. Astellas is an R&D-driven global pharmaceutical company whose philosophy is to contribute to the improvement of people's heath around the world through the provision of innovative and reliable pharmaceutical products. AIRM has a world-class R&D team, and is pursuing a diverse range of disease indications, ranging from macular degeneration (currently in clinical trials) and other ocular indications to vascular and autoimmune disease. AIRM's intellectual property portfolio includes pluripotent stem cell platforms -- both embryonic and induced pluripotent stem cells as well as other cell-based therapy research programs. AIRM is headquartered in Massachusetts. Astellas is announcing a Senior Research Associate/Scientist I opportunity at their Astellas Institute for Regenerative Medicine (AIRM) site in Westborough, MA. Purpose:We are seeking a Senior Research Associate/Scientist I (level commensurate with experience/ qualifications) to participate in discovery-based research of pluripotent stem cell-derived pipeline products for indications in ophthalmology. The incumbent will play an integral role working as part of the in vivo retina team and interface with other members of Research and other departments. Essential Job Responsibilities:Hands-on participation in rodent in vivo ocular cell therapy transplantation studies carrying out in vivo procedures as well as ex vivo analyses of harvested tissues (e.g. retinas), either independently or alongside other colleagues. This may involve any of the following laboratory techniques: all aspects of surgery for subretinal or intravitreal injections, fundus imaging, OCT, optomotor response (OMR/OKT), electroretinogram (ERG), histological tissue harvest/processing, immunohistochemistry, mouse behavioral studies, and ex vivo multielectrode recordings.Assist with maintenance of mouse and rat colonies, including timed breeding.Execute procedures and protocols with guidance and have the ability to summarize results independently.Collaborate closely and collegially within the team and across functional groups to advance pipeline programs.Maintain accurate records in laboratory notebooks, appropriate databases, and inventories in a timely manner.Must be able to work flexible hours, occasionally on weekends. Quantitative Dimensions:With guidance, independently and efficiently perform laboratory experiments to advance departmental pipeline programs.Excellent communication and interpersonal skills to work effectively in a collaborative environment. Organizational Context:Reports to Director of Research (In Vivo Retina Team) PDN-990b160a-8e9f-4e80-b97d-4acd858badb2

Keywords: Astellas, Worcester , Senior Research Associate, In Vivo, Other , Westborough, Massachusetts