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Scientist I/II, Protein Analytics (Characterization)

Company: AbbVie
Location: Worcester
Posted on: October 14, 2019

Job Description:

Our Protein Analytics Department is searching for an innovated and motivated Scientist to join our Analytical Characterization Group (ACG) at the AbbVie Bioresearch Center in Worcester, MA. Our ACG is responsible for the structural characterization of a range of biotherapeutic agents in support of the development and registration of AbbVie's biologic pipeline of preclinical, clinical and commercial products! As a key member of our team, you will have opportunity to develop and perform state-of-art mass spectrometric and biophysical characterization assays for various programs of protein biologics! Key Responsibilities: Develop biophysical characterization methods such as CD, DSC, etc. Perform intact and subunit mass spectrometric analysis to programs such as monoclonal antibodies, ADCs and other biotherapeutic modalities Execute peptide mapping LC-MS analysis for detailed structure characterization of protein biologics such as sequence verification and PTM analysis Effectively interact with group members and across departments to understand project background and testing requirement Capture analytical data and scientific findings in ELNs; share results at group meetings and with project teams Draft technical memos, characterization reports and support regulatory filings Maintain lab equipment and contribute to team culture of mutual respect and collaboration Position will be hired based on level of experience. Bachelors or masters in chemistry, biology, biochemistry or related field with typically 5+ (BS) or 2+ (MS) years of relevant experience; Industry experience preferred Hands-on experience with mass spectrometry, chromatography, electrophoresis, protein biophysical characterization and other analytical techniques desired Experience in structural characterization of protein biotherapeutic agents is preferred Inventive, hardworking with attention to both efficiency and quality of work Ability and willingness to work with other scientists and partners cooperatively to ensure project progress within timeline

Keywords: AbbVie, Worcester , Scientist I/II, Protein Analytics (Characterization), Other , Worcester, Massachusetts

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