Principal Research Scientist II

Company: AbbVie
Location: Worcester
Posted on: January 16, 2026

Job Description:

Company Description AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on X , Facebook , Instagram , YouTube , LinkedIn and Tik Tok . Job Description Purpose: The Cell Culture Development organization within Operations leads the process development and tech transfer of cell culture processes for clinical manufacturing and commercialization of therapeutic proteins in the AbbVie pipeline. In addition, we provide subject matter expertise and experimental support for the manufacture of commercial biologics. A successful candidate would be one of the senior leaders in the Cell Culture Development group and would be responsible for guiding a team of scientists and engineers in the definition and resolution of complex challenges presented by AbbVies robust, diverse biologics pipeline. The candidate would be expected to work together with cell culture scientists at AbbVie Bioresearch Center and other AbbVie sites to define and implement strategies for pre-clinical, early and late stage cell culture development and to identify and prioritize scientific and technological opportunities for investment that will result in robust, high-yielding processes. Responsibilities: Leads a group of 5 scientists and engineers with BS/MS and PhDs focused on bioprocess modeling, PAT and advanced bioreactor monitoring and control. Leads cell culture process development for monoclonal antibodies, bi-specifics, ADCs, fusion proteins and other molecular formats for early and late-stage clinical assets. Leads PPQ enabling cell culture process characterization activities. Leads/participates in cross-functional CMC teams and reviews relevant sections of regulatory submissions (e.g. IND, BLA, MAA, etc.). Advances technical expertise within the cell culture development field. Tracks emerging trends and technologies within the field through internal and external sources, assesses their relevance to AbbVie and facilitates their internal adoption by effectively communicating their value to the business. Pro-actively advises and shares knowledge with the team, peers and senior management. Mentor and enhance staff performance to create a climate of excellence to achieve business and scientific objectives. Develops, communicates and implements a vision for development of strategic capabilities. Identifies and drives technical innovations that will contribute to future business developments and improvements. Qualifications Bachelors Degree inBiology, Biochemistry, Chemical Engineering or related fieldwith 16 years of related work; Masters Degree Science or PharmD with 14 years of related work; PhD in Science or related field with 8 years of related work experience. Exceptional candidates with less experience will be considered. Outstanding record of accomplishment in the Biotech and/or Biopharmaceutical field. Proven ability to innovate with a history of new or improved product releases. Has demonstrated the ability to lead scientists and engineers through urgent situations by developing actionable goals and robust implementation plans. Interacts well with diverse groups within function and maintains strong working relationships with internal and external collaborators. Must have a results oriented work ethic and a positive, can-do attitude. Excellent written and oral communication skills are expected. Preferred Qualifications: Demonstrated proficiency in bench scale bioreactor, shake flask, and other culture systems for the optimization of cell culture processes. Experience with or ability to lead a team with focus on development and application of hybrid, machine learning, mechanistic and other advanced modelling techniques. Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law: The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at thetimeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location,andwemay ultimatelypay more or less than the posted range. This range may be modified in thefuture. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees. This job is eligible to participate in our short-term incentiveprograms. Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of anybonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's soleandabsolutediscretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent withapplicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html

Keywords: AbbVie, Worcester , Principal Research Scientist II, Science, Research & Development , Worcester, Massachusetts